Endocrine Abstracts

Background: Metabolic syndrome (MS) in children is associated with future risk of developing type 2 diabetes mellitus and cardiovascular disease in adults. In the pediatric population lifestyle interventions alone are often insufficient.Objective: To evaluate the efficacy and safety of orlistat in obese adolescents with MS.Design: A 6 month open, comparative, randomized study of 60 obese adolescents (aged 12–17 years; mean bod...